diff --git a/.github/workflows/e2e-tests.yml b/.github/workflows/e2e-tests.yml
index 06b8e514062..6a8715514db 100644
--- a/.github/workflows/e2e-tests.yml
+++ b/.github/workflows/e2e-tests.yml
@@ -372,6 +372,13 @@ jobs:
               OUTPUT=$(../bashunit -a exit_code "1" "../../bin/phpstan analyse -vv --error-format raw")
               echo "$OUTPUT"
               ../bashunit -a contains 'ClassUsingConstant.php:13:Constant SOME_MODE not found. [identifier=constant.notFound]' "$OUTPUT"
+          - script: |
+              cd e2e/result-cache-define
+              ../../bin/phpstan analyse
+              patch -b src/define.php < changeDefineValue.patch
+              OUTPUT=$(../bashunit -a exit_code "1" "../../bin/phpstan analyse -vv --error-format raw")
+              echo "$OUTPUT"
+              ../bashunit -a contains 'ClassUsingDefine.php:13:Method ResultCacheE2EDefine\ClassUsingDefine::getMode() should return int<1, 3> but returns 5. [identifier=return.type]' "$OUTPUT"
           - script: |
               cd e2e/bug-12606
               export CONFIGTEST=test
diff --git a/e2e/result-cache-define/changeDefineValue.patch b/e2e/result-cache-define/changeDefineValue.patch
new file mode 100644
index 00000000000..43836f76965
--- /dev/null
+++ b/e2e/result-cache-define/changeDefineValue.patch
@@ -0,0 +1,7 @@
+--- src/define.php
++++ src/define.php
+@@ -1,3 +1,3 @@
+ <?php
+ 
+-define('SOME_DEFINED_MODE', 1);
++define('SOME_DEFINED_MODE', 5);
diff --git a/e2e/result-cache-define/phpstan.neon b/e2e/result-cache-define/phpstan.neon
new file mode 100644
index 00000000000..1796e7715c7
--- /dev/null
+++ b/e2e/result-cache-define/phpstan.neon
@@ -0,0 +1,5 @@
+parameters:
+	level: 8
+	paths:
+		- src
+	tmpDir: tmp
diff --git a/e2e/result-cache-define/src/ClassUsingDefine.php b/e2e/result-cache-define/src/ClassUsingDefine.php
new file mode 100644
index 00000000000..0be1dd41c52
--- /dev/null
+++ b/e2e/result-cache-define/src/ClassUsingDefine.php
@@ -0,0 +1,16 @@
+<?php
+
+namespace ResultCacheE2EDefine;
+
+class ClassUsingDefine
+{
+
+	/**
+	 * @return int<1, 3>
+	 */
+	public function getMode(): int
+	{
+		return SOME_DEFINED_MODE;
+	}
+
+}
diff --git a/e2e/result-cache-define/src/define.php b/e2e/result-cache-define/src/define.php
new file mode 100644
index 00000000000..e5a86fdac80
--- /dev/null
+++ b/e2e/result-cache-define/src/define.php
@@ -0,0 +1,3 @@
+<?php
+
+define('SOME_DEFINED_MODE', 1);
diff --git a/e2e/result-cache-define/tmp/.gitignore b/e2e/result-cache-define/tmp/.gitignore
new file mode 100644
index 00000000000..125e34294bf
--- /dev/null
+++ b/e2e/result-cache-define/tmp/.gitignore
@@ -0,0 +1,2 @@
+*
+!.*
diff --git a/src/Dependency/ExportedNodeResolver.php b/src/Dependency/ExportedNodeResolver.php
index 1e230374a0f..d071479c911 100644
--- a/src/Dependency/ExportedNodeResolver.php
+++ b/src/Dependency/ExportedNodeResolver.php
@@ -240,6 +240,25 @@ public function resolve(string $fileName, Node $node): ?RootExportedNode
 			return new ExportedConstantsNode($constants);
 		}
 
+		if (
+			$node instanceof Node\Expr\FuncCall
+			&& $node->name instanceof Name
+			&& $node->name->toLowerString() === 'define'
+		) {
+			$args = $node->getArgs();
+			if (
+				isset($args[0], $args[1])
+				&& $args[0]->value instanceof Node\Scalar\String_
+			) {
+				return new ExportedConstantsNode([
+					new ExportedConstantNode(
+						$args[0]->value->value,
+						$this->exprPrinter->printExpr($args[1]->value),
+					),
+				]);
+			}
+		}
+
 		return null;
 	}